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Using two separate drugs to shed weight can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it one should err assisting caution and let the FDA do its job and demand some study be done so that the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies will be in business to generate income and that they would say almost anything to keep people on his or her medications. Researchers found out that participants investing in this drug to get a year, dropped excess weight within 4 weeks and have kept the weight off during the entire 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which might be made up of more than one active ingredient, which might make them more efficient and safer. Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular is the fact that at the time of right now there are not any long term prescription slimming capsules that have been authorized by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure levels and pulse rate, and must not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not used in patients with uncontrolled high blood pressure, as well as by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients for the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. 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