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Using two separate drugs to shed pounds can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err to the side of caution and allow the FDA do its job and demand some investigation be done so that the public understands the side effects and risks of the medications before we drive them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on the medications. Researchers discovered that participants taking this drug for the year, dropped excess weight within a month and have kept the extra weight off throughout the 56 weeks of the study. Contrave is really a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of more than one active ingredient, which can make them far better and safer. Combo-pilling may be the newest fad or better yet the newest to come under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that as of right now there aren't long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug can also raise blood pressure level and heartbeat, and really should not be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients for the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. "This may be the first drug I'm alert to that targets both appetite and reward centres inside brain," he was quoted saying.